The Gene and Linda Voiland School of Chemical Engineering and Bioengineering is hosting a seminar presented by Helena Zomer, Visiting Graduate Student, Department of Bioengineering, University of Washington, Feb. 12, at 4:10 p.m. in ADBF 1002/FLOYD 256 (Tri-Cities).
Helena Zomer holds a degree in Veterinary Medicine and a Master in Science in the field of anatomy of domestic and wild animals. Zomer is a PhD student under supervision of Prof. Trentin in the Laboratory of Stem Cells and Tissue Regeneration from the Department of Cell Biology, Embriology and Genetic at Federal University of Santa Catarina, Brazil. Currently she is a visiting graduate student at University of Washington – Seattle, under supervision of Prof. Buddy Ratner. Zomer is interested in stem cells, regenerative medicine, tissue engineering, animal models and translational research.
INFLUENCE OF THE SOURCE OF MESENCHYMAL STEM CELLS FOR TISSUE ENGINEERING: DERMAL VERSUS ADIPOSE TISSUE IN SKIN WOUND HEALING
Large skin wounds such as burns lead to secondary disorders and death if not quickly stabilized. Novel strategies combining cell therapy, tissue engineering and regenerative medicine have been developed to treat these challenging wounds. Currently, the gold standard treatment involves using dermal templates, such as Integra matrix, a dermal substitute composed by collagen and chondroitin sulfate. Mesenchymal stromal cells (MSC) shows wide therapeutic application due its differentiation potential and paracrine effects. Despite sharing stemness characteristics as self-renew, differentiation to mesodermal tissues and immunophenotype, MSC from distinct niches can present individual features. Therefore, studying diverse sources of MSC is important to develop future therapeutic approaches. This study comparatively characterized MSC from human abdominal dermis (DSC) and adipose tissue (ASC) and evaluate their association with Integra matrix in skin wound healing.
