The Department of Translational Medicine and Physiology welcomes Dr. Shobhan Gaddameedhi, associate professor in the Department of Biological Sciences at NC State University to WSU Spokane on Tuesday, April 29. He will be providing his seminar at 12:10 p.m., “Circadian Disruption, Genomic Instability, and Their Effects on Cancer and Cardiotoxicity,” at WSU Spokane, SAC 347 and via Zoom.
Do you sometimes wonder how your body knows when it is time to sleep or wake up? Every cell in our body is programmed with a biological, also called a ‘circadian’ clock, that aligns our bodies with the day and night cycles of the earth. This clock controls numerous biological processes on a 24-hour cyclical rhythm of activity and rest. These processes range from fundamental biochemical and cellular events such as cell cycle, DNA repair, and inflammation to functional physiological events like sleep wake cycles and metabolism. In this talk, I will highlight the recent findings of how the circadian clock regulates genomic stability through DNA repair and melanin pigmentation. In addition, this presentation will highlight the mechanisms by which circadian clock disruption influences cancer and cardiotoxicity outcomes.
We look forward to you joining us in person (SAC 347) or through Zoom!
Questions/Zoom link? Contact Michelle Sanchez at michelle.r.sanchez@wsu.edu.
