The Department of Translational Medicine and Physiology welcomes Dr. Benjamin Weaver, UT Southwestern Medical Center, to WSU Spokane on Tuesday, Oct. 8. He will be providing his seminar at 12:10 p.m., “Caspase-Mediated Regulation of Stress Responses,” in SAC 347 and via Zoom.
Chronic stress and inflammation are major risk factors for disease. Heightened stress responses suggest a failure to sense resolution of the stressor. Recently, we found that proteolytic cleavage of limited amounts of fatty acid synthase (FASN) releases a stable C-terminal fragment (FASN-CTF) that promotes an anti-inflammatory program including gene expression, metabolic programs and lipid droplets. Our current findings resolve how caspase is differentially regulated in stress responses versus cell death.
The Weaver lab combines cross-disciplinary approaches using genetics, proteomics, metabolomics and biochemical analyses along with diverse models including C. elegans, mammalian cell culture, and in vitro systems.combines cross-disciplinary approaches using genetics, proteomics, metabolomics and biochemical analyses along with diverse models including C. elegans, mammalian cell culture, and in vitro systems.
We look forward to you joining us in person (SAC 347) or through Zoom!
Questions/Zoom link? Contact Michelle Sanchez at michelle.r.sanchez@wsu.edu.
